Dancing protein clouds: Intrinsically disordered proteins in health and disease, Part A
| By: | Author |
| Publisher: | Elsevier S & T |
| Print ISBN: | 9780128168516 |
| eText ISBN: | 9780128168523 |
| Edition: | 0 |
| Copyright: | 2019 |
| Format: | Reflowable |
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"Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain.
- Provides some recent studies on the intrinsically disordered proteins and their functions, as well as on the involvement of intrinsically disordered proteins in pthogenesis of various diseases
- Contains numerous illustrative materials (color figures, diagrams, and tables) to help the readers to delve in the information provided
- Includes contributions from recognized experts in the field