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Cover image for book Mechanisms of Lymphocyte Activation and Immune Regulation XI

Mechanisms of Lymphocyte Activation and Immune Regulation XI

B Cell Biology
By:Sudhir Gupta; Frederick W. Alt; Max D. Cooper
Publisher:Springer Nature
Print ISBN:9780387465272
eText ISBN:9780387465302
Edition:1
Copyright:2007
Format:Page Fidelity

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In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.