Cellular Senescence and Tumor Suppression
| By: | Peter D. Adams; John M. Sedivy |
| Publisher: | Springer Nature |
| Print ISBN: | 9781441910745 |
| eText ISBN: | 9781441910752 |
| Edition: | 1 |
| Copyright: | 2010 |
| Format: | Reflowable |
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As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.