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Cover image for book Phosphoinositide 3-kinase in Health and Disease

Phosphoinositide 3-kinase in Health and Disease

Volume 2
By:Christian Rommel; ‎Bart Vanhaesebroeck; ‎Peter K. Vogt
Publisher:Springer Nature
Print ISBN:9783642148156
eText ISBN:9783642148163
Edition:1
Copyright:2011
Format:Reflowable

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PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impact of intervention with PI3K activity are high, and progress in the clinical arena is being monitored by many. However, targeted therapies almost invariably encounter roadblocks, often exposing unresolved questions in the basic understanding of the target