PEGylated Protein Drugs: Basic Science and Clinical Applications
| By: | Francesco M. Veronese |
| Publisher: | Springer Nature |
| Print ISBN: | 9783764386788 |
| eText ISBN: | 9783764386795 |
| Edition: | 0 |
| Copyright: | 2009 |
| Format: | Page Fidelity |
Lifetime - $261.25
eBook Features
Instant Access
Purchase and read your book immediately
Read Offline
Access your eTextbook anytime and anywhere
Study Tools
Built-in study tools like highlights and more
Read Aloud
Listen and follow along as Bookshelf reads to you
Details
Table of Contents
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.